Tumor Marker Tests

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Assure Tech (Hangzhou) Co., Ltd was established by senior experts of in the in-vitro diagnostics industry in 2008. As a high-tech biotechnology company, Assure Tech is specialized in research & development, production, sales of diagnostic reagents, POCT and biological materials.

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What Is Tumor Marker Tests?

A tumor marker is any substance in your body that provides information about a cancer. Traditionally, tumor markers refer to proteins that cancer cells make. Noncancerous cells can also make tumor markers in response to a cancer. But a tumor marker can also refer to mutations (changes) or patterns in your DNA.

Benefits Of Tumor Marker Tests

Early Detection

These tests aid in the early identification of certain cancers, even before symptoms manifest. Early detection often leads to more successful treatment outcomes.

Diagnosis

Elevated levels of specific markers can signal the presence of cancer. However, a definitive diagnosis is typically achieved through further evaluations such as imaging and biopsies.

Monitoring

Tumor marker tests enable the monitoring of treatment progress. Changes in marker levels over time provide insights into the effectiveness of therapies.

Recurrence Detection

After successful treatment, these tests help detect any cancer recurrence or the reappearance of cancer cells.

Prognosis

Tumor marker levels offer insights into the probable course of the disease, aiding in predicting its trajectory.

Treatment Response

Changes in marker levels indicate whether a chosen treatment is halting tumor growth or even causing regression.

Types of tumor marker tests

AFP (Alpha-fetoprotein): Using a sample of your blood, healthcare providers may look for this as they consider diagnoses of liver cancer, testicular cancer and other germ cell tumors, and to determine the success of treatment.

BCL2 gene rearrangement: Using a sample of your blood, bone marrow or tumor, healthcare providers may look for this as they diagnose and plan treatment for cancers like leukemia and lymphoma.

BRCA1 and BRCA2 gene mutations: Using a sample of your blood, saliva or tumor, healthcare providers may look for this as they diagnose and plan for screening and treatment of breast cancer and ovarian cancer.

CA 19-9: Using a sample of your blood, healthcare providers may look for this as they diagnose and evaluate the success of treatment for cancer of the pancreas, gallbladder, bile duct and stomach.

Carcinoembryonic antigen (CEA): Using a sample of your blood, healthcare providers may look for this if you have colon cancer as they determine the success of treatment or whether the cancer has spread or come back.

Fibrin/fibrinogen: Using a sample of your urine, healthcare providers may look for this to determine the success of treatment for bladder cancer.

Lactate dehydrogenase (LDH): Using a sample of your blood, healthcare providers may look for this to stage or determine the success of treatment for leukemia, lymphoma, melanoma, neuroblastoma and germ cell tumors.

Prostate-specific antigen (PSA): Using a sample of your blood, healthcare providers may look to help diagnose prostate cancer, determine the success of treatment or check to look if it's returned.

Thyroglobulin: Using a sample of your blood, healthcare providers may look for this if you've had thyroid cancer. They use it to determine how successful treatment has been or to check to see if the cancer came back.

UGT1A1*28 variant homozygosity: Using a sample of your blood or a cheek swab, healthcare providers may look for this if you have colorectal cancer. They use it to predict how sick you'll get (toxicity) from a chemotherapy drug called irinotecan.

How are tumor markers measured?

A doctor takes a sample of tumor tissue or bodily fluid and sends it to a laboratory, where various methods are .used to measure the level or presence (or absence) of the tumor marker.If the tumor marker is being used to determine whether treatment is working or whether there is a recurrence,the marker's level will be measured in multiple samples taken at different times during and after treatment.Usually "serial measurements," which show how the level of a marker is changing over time, are more meaningful than a single measurement.Some markers, such as the presence or absence of a particular genetic alteration that makes a tumor a candidate for treatment with a specific targeted therapy, do not themselves change over time. However, theproportion of tumor cells that have that alteration may change during and after treatment.

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FAQ

Q: What does it mean if you have a tumor marker?

A: A tumor marker is any substance in your body that provides information about a cancer. Traditionally, tumor markers refer to proteins that cancer cells make. Noncancerous cells can also make tumor markers in response to a cancer. But a tumor marker can also refer to mutations (changes) or patterns in your DNA.

Q: Do cancer markers show up in routine blood work?

A: Aside from leukemia, most cancers cannot be detected in routine blood work, such as a CBC test. However, specific blood tests are designed to identify tumor markers, which are chemicals and proteins that may be found in the blood in higher quantities than normal when cancer is pr

Q: Should I be worried about tumor markers?

A: Tumor marker tests can provide a lot of helpful information, but they aren't fail-safe. Just because a person has tumor markers, it doesn't always mean cancer is present or has come back. Conditions besides cancer can raise tumor marker levels.

Q: Is a Tumour marker serious?

A: High tumor marker levels can be a sign of cancer. Along with other tests, tumor marker tests can help doctors diagnose specific types of cancer and plan treatment. Tumor marker tests are most commonly used to do the following: Learn if a person has cancer.

Q: Do all cancers have tumor markers?

A: Not all cancers have known tumor markers. And the tumor markers that are known don't provide perfect information. That's because: Some conditions that aren't cancer may also cause high levels of certain tumor markers.

Q: What blood test detects early cancer?

A: Introducing Galleri®, the first-of-its-kind multi-cancer early detection test that looks for a signal shared by 50+ types of cancer with a single blood test. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur.

Q: What is the hardest cancer to detect?

A: Pancreatic cancer is hard to find early. The pancreas is deep inside the body, so early tumors can't be seen or felt by health care providers during routine physical exams. People usually have no symptoms until the cancer has become very large or has already spread to other organs.

Q: What happens when tumor markers go up?

A: An increase in tumour marker levels may mean the cancer is not responding to treatment, is growing or has come back (recurred). A slight increase may not be significant. The doctor looks at trends in the increase over time. Chemotherapy treatment can cause a temporary increase in tumour marker levels.

Q: Is it normal to have tumor markers?

A: Tumor markers are substances found in the blood. Tumor marker levels may be higher when there is cancer in the body. They are not very “specific,” meaning non-cancer health issues can also cause these levels to be higher. They must be used along with radiology tests and exams by your healthcare provider.

Q: What is the normal range for tumor markers?

A: Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

Q: What is the number 1 symptom of cancer?

A: Lump or area of thickening that can be felt under the skin. Weight changes, including unintended loss or gain. Skin changes, such as yellowing, darkening or redness of the skin, sores that won't heal, or changes to existing moles. Changes in bowel or bladder habits.

Q: What are red flags of a cancer?

A: Other symptoms, such as weight loss or fever, develop only after the cancer progresses. Still other symptoms, such as a change in bowel habits, blood in the stool, or swallowing difficulty, are signs of cancer in specific sites of the body.

Q: What test shows all cancers?

A: There is no single test that can diagnose cancer. So your doctor may start by asking about your personal and family medical history and doing a physical exam. They may order lab tests, imaging tests (scans), or other tests or procedures.

Q: Can inflammation cause tumor markers to rise?

A: Inflammation can affect tumor development and progression in addition to the response to therapy. Cytokines are mediators that govern a vast range of processes involved in the development of cancer, and markers of inflammation form a major part of the tumor microenvironment.

Q: What cancers does CA-125 detect?

A: This blood test checks for raised levels of a protein called CA125. It helps diagnose or monitor ovarian, fallopian tube or primary peritoneal cancer. You may have a CA125 blood test during diagnosis or after treatment for ovarian cancer, fallopian tube cancer or primary peritoneal cancer.

Q: What is the best blood test to detect cancer?

A: A complete blood count (CBC) is a common medical test that your doctor may recommend to monitor your health. In cancer care, this blood test can be used to help diagnose a cancer or monitor how cancer or its treatment is affecting your body. For example, people undergoing chemotherapy often receive regular CBCs.

Q: Can a CT scan detect cancer?

A: CT scans play many different roles in the diagnosis and treatment of cancer. Screening: CT is sometimes used to screen for different types of cancer, such as lung and colorectal cancer. Diagnosis: Your doctor may order a CT scan to locate and size suspected tumors.

Q: What are the top 3 deadliest cancers?

A: Lung and bronchus, colorectal, pancreatic, and breast cancers are responsible for nearly 50% of all deaths.

Q: Which cancers spread the fastest?

A: Which Type of Cancer Spreads Fastest? The fastest-moving cancers are pancreatic, brain, esophageal, liver, and melanoma. Pancreatic cancer is one of the most dangerous types of cancer because it's fast-moving, and there's no method of early detection.

Q: Can stress increase tumor markers?

A: Can stress cause tumor markers to rise? Research suggests that chronic stress may cause cancer to spread faster or recur (come back) in people who've had cancer in the past. Tumor markers-in combination with other diagnostic tools-help healthcare providers diagnose, treat and monitor certain types of cancer.

We're well-known as one of the leading tumor marker tests manufacturers and suppliers in China. Please feel free to buy bulk high quality tumor marker tests at competitive price from our factory. For more information, contact us now.

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